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How much trazodone will kill you?
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How much trazodone will kill you?
benefit; in short-term studies of antidepressants vs. Trusted by business builders. While pharmacotherapy should not be the sole treatment for insomnia, medication may be part of an integrated approach that includes behavioral strategies and treatment of relevant comorbidities. Inpatient: No more than 600 mg/day Trazodone (Desyrel - discontinued) treats depression, panic attacks, cocaine withdrawal, and aggressive behavior. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. I know these words will be of empty comfort to you as you look for answers to a loved one’s sui I’m sorry. Trazodone is an oral psychoactive agent that is FDA indicated for the treatment of depression. However, trazodone can be used on an as-needed basis with a fast onset as long as you are not using extended-release tablets. Do not chew or crush trazodone hydrochloride tablets. The maximum recommended dose for depression is 400 mg per day. Trazodone hydrochloride overdose. You might also feel very drowsy and vomit. Buy Trazodone Tablets Online - Free Worldwide Shipping Trazodone is an oral state of mind elevator considered depression, anxiety (when it's a sign of misery), in addition to for agoraphobia, panic strikes and boosted aggressiveness. You should talk about this possibility with your health care provider. View Trazodone's uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg Convenient delivery: With online purchasing, you can have Trazodone delivered directly to your doorstep. Although it is FDA-approved only for use in the treatment of major depression, trazodone, a drug created in the 1960s [], is widely used off-label to control agitation and insomnia in Alzheimer’s disease (AD) [] and in anxiety, schizophrenia, bulimia, substance abuse, fibromyalgia [], and post-traumatic stress disorder [1, 4]. The best way to kill grass without chemicals or machinery is to cover the area with layers of newspapers, according to About The newspapers break down after several months, mi. Antidepressants like trazodone help to improve your mood so you feel better. traZODone Pharmacokinetics Absorption Bioavailability. What does Trazodone hydrochloride look like? Trazodone withdrawal increases the heart rate by up to 128 per minute. This means that every 5 to 13 hours, the level in your blood will drop by 50 percent. If you take it once a day, it's best to take it in the evening or before you go to bed. Advertisement In "The Calculus Affair," one of the volumes in He. Trazodone is rapidly absorbed in the gastrointestinal tract after oral administration, with a bioavailability ranging from 63-91% 9 and an AUC0−t of 18193 17 Food may impact absorption in a variable fashion, and may sometimes lead to decreases in the Cmax of trazodone. How it affects you will depend on the type of antidepressant, how much is taken, and if it's mixed with other drugs or alcohol. Taking too much of. If you become pregnant during treatment with trazodone hydrochloride tablets, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants. Do not drive or operate machinery until you know how trazodone affects you. Published: December 5, 2023. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared with placebo in. Don't wait until the symptoms get worse. Trazodone, also know by brand names “Desyrel” and “Oleptro,” is an antidepressant medication that is used to treat major depressive disorders. While the potential for trazodone abuse is fairly low, any amount over 600 mg. CYP3A4 enzyme inhibitors (e, clarithromycin, nefazodone, ketoconazole): may lead to the person requiring a lower dose of trazodone; trazodone toxicity may occur at smaller-than-usual dosesg. It comes in 50 mg, 100 mg, 150 mg, and 300 mg scored white, round tablets. Trazodone overdose occurs when someone takes more than the normal or recommended amount of this medicine, either by accident or on purpose. There are 650 drugs known to interact with trazodone, along with 8 disease interactions, and 1 alcohol/food interaction. For trazodone the half-life is approximately 5 to 13 hours. In this low-dose range, trazodone is thought to help encourage sleep while limiting the risk of daytime sleepiness. This review describes trazodone mechanism of action, formulation, dosage and adverse effects and then summarizes the beneficial effects of trazodone in the treatment of various. It can occur when you take too much trazodone or when you combine it with other serotonergic medications, such as SSRIs like Zoloft, Lexapro, and Prozac, MAOIs like Marplan, Nardil, and Parnate, triptans, and fentanyl. What should I do if I accidentally use too much trazodone? If you or someone else has used too much trazodone, get medical help right away, call 911, or contact a Poison Control center at 800-222. Learn how to avoid this rookie mistake. Depression is a major public health problem and is the leading cause of disability in the United States and worldwide []. Vomiting Trazodone overdose can also lead to serotonin syndrome, a condition characterized by excessive accumulation of serotonin in the body. While it is important to use bleach safely. If you need a handy way to kill weeds, especially those that grow in sidew. Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. - Cytochrome P450 3A inhibitors and inducers - Cytochrome P450 2D6 (CYP2D6) inhibitors - Side effects of antidepressant medication - Serotonin syndrome agents - Pharmacology antidepressants Trazodone is not a benzodiazepine, according to Drugs Trazodone is an antidepressant that treats chemical imbalances in the brain that are known to lead to major depressive di. Tell your healthcare provider if you cannot swallow trazodone either whole or as a half tablet. Trazodone is a serotonin antagonist and reuptake inhibitor—not a narcotic. The use of alcohol or cannabis may increase the adverse effects of trazodone, especially those related to psychomotor disturbances. If you are taking trazodone for the treatment of depression, it generally takes at least 4 to 6 weeks to realize the full effects of the drug. 1 Sleep disorders are extremely common, affecting about 30% of the general population worldwide [1,2]. Bug zappers seem logical: bugs fly toward light, so why not hang up a light that kills the bugs and enjoy a bug-free evening? Unfortunately, the bugs you’re targeting aren’t actual. Meta is killing its Messenger for Apple Watch app on May 31, the company confirmed to TechCrunch on Thursday. Trazodone also is described as a serotonin modulator. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. Initial 150 mg/day PO divided q8-12hr. In general, the more of Trazodone you ingest, the longer you can expect to retain the drug (and its metabolites) in your system. When using trazodone for sleep, the drug is given at low doses—typically between 25 to 100 milligrams (mg)—which reduces the risk of drug tolerance and daytime sleepiness. Weeds are the bane of every home gardener and lawn care enthusiast. Overdosing on trazodone is more likely if you're taking other medications that can cause drowsiness or affect your heart rhythm. Toggle navigation Toggle search Close. Trazodone is used in the treatment of Depression. Trazodone is a member of the phenylpiperazine antidepressants drug class and is commonly used for Anxiety, Depression, Fibromyalgia, and others The cost for trazodone 100 mg oral tablet is around $19 for a supply of 30 tablets, depending on the pharmacy you visit. If you suspect that someone you care about may be chronically misusing trazodone, a blood test, hair test, saliva drug test, or urine test can approximate when the drug was last. Includes TraZODone indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse. Absorption. Trazodone, also know by brand names "Desyrel" and "Oleptro," is an antidepressant medication that is used to treat major depressive disorders. This information from Lexicomp explains what you need to know about this medication, including what it's used for, how to take it, its side effects, and. Note that this list is not all-inclusive and includes only common medications that may interact with trazodone You should refer to the prescribing information for trazodone for a complete list of interactions. in pts 65 yo and older; depression and certain other psychiatric disorders themselves assoc suicide risk; observe all. Trazodone is an antidepressant medicine. Trazodone has severe interactions with at least 17 other drugs. This medicine is available only with your doctor's prescription. Trazodone can impair judgment, thinking, and motor skills. Here are some tips to safely and effectively. Much lower doses produce toxic symptoms when combined with other drugs. If you believe you have a medical emergency, you should immediately call 911. Maximum dose: Inpatients: 600 mg/day. The maximum recommended dose for depression is 400 mg per day. Bug zappers seem logical: bugs fly toward light, so why not hang up a light that kills the bugs and enjoy a bug-free evening? Unfortunately, the bugs you’re targeting aren’t actual. The Glow is hardly the first experimental product Amazon has killed off over the years, as the company regularly tests its hardware ideas. Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (trazodone extended-release tablets) affects you Take trazodone in the evening and try to cut down the amount of alcohol you drink. Much like its effect on depression, trazodone can take multiple weeks to work for anxiety. Surface and sub-soil tree roots become problems when they invade sewers, create cracks in sidewalks and rise prominently in your yard. Combining this blood pressure drug (also known as Zestril or Prinivil) with potassium can cause irregular heart rhythms or death. The dosage for trazodone depends on what conditions the patient is being treated for. It may take up to 3 weeks before you will notice the effect of Trazodone. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. Self-poisoning is a common method of suicide, especially in women. Change from baseline of the Brief Pain Inventory Short Form (BPI-SF) item 6 in the intention-to-treat with last observation carried forward population. jamestown sun This is a low risk for switch to mania during treatment with sleep-promoting antidepressants. Treatment Hotline Free & Confidential 24/7 (800) 913-1755 (800) 913-1755 Find Rehab. Trazodone is a serotonin antagonist and reuptake inhibitor—not a narcotic. In this article, we will discuss the potential risks and side effects of trazodone in dogs, and provide some tips on how to use this medication safely. INTRODUCTION. The antidepressant trazodone can kill your cat within a few minutes. Talk to your healthcare provider about the risk to your unborn baby if you take trazodone hydrochloride tablets. symptoms of overdose. Some people kill animals because they want to use the animals for food or clothing, while other people kill animals because they find it challenging and fun. Learn more about how trazodone is compared to ambien as a sleeping pill. This is true for the vast majority of antidepressant. 1 When administered in combination with tricyclic antidepressants or selective serotonin reuptake inhibitors, it is recommended to begin dosing trazodone at 2. Check with your doctor before taking a non-steroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling Trazodone's preferential prescription may be related to its perception as a safer substitute for other hypnotics. Trazodone is available in tablets of 50, 75, 100, 150 and 300 mg in several generic forms and formerly under the brand name Desyrel. This article is for information only. The dosage of trazodone varies depending on what it is being used for. Antidepressants like trazodone are used to ease symptoms such as low mood, poor sleep and poor concentration. In this article, we will discuss the potential risks and side effects of trazodone in dogs, and provide some tips on how to use this medication safely. INTRODUCTION. In the US -Call your doctor for medical advice about side effects. The drug later gained various off-label (non-approved) uses, including in the treatment of anxiety, bulimia, chronic pain, dementia. The prescribing information for trazodone states the following: GoodRx works to make its website accessible to all, including those with disabilities. what's the score of the brewers game If you take too much trazodone hydrochloride, call your healthcare provider, your poison control center at 1-800-222-1222, or go to the nearest emergency room right away. AG-Trazodone; APO-TraZODone; APO-TraZODone D; JAMP-Trazodone; PMS-TraZODone; TEVA-TraZODone; TraZODone-100; TraZODone-150; Thus, your vet will advise whether you need to give a dog trazodone regularly or only when he requires it. Do not drive or operate machinery until you know how trazodone affects you. You may report side effects to FDA at 1-800-FDA-1088. Assuming you were to take a single dose of 50 mg, you'd likely be able to metabolize and excrete this dose substantially quicker than a 300 mg dose. Trazodone overdose occurs when someone takes more than the normal or recommended amount of this medicine, either by accident or on purpose. Trazodone is commonly prescribed to dogs to help manage anxiety, aggression, and other behavioral issues. What happens if you take too much trazodone? Can it cause serotonin syndrome? Trazodone (brand name Desyrel, Oleptro) is a medication used to treat depression in people. Vomiting Trazodone overdose can also lead to serotonin syndrome, a condition characterized by excessive accumulation of serotonin in the body. What is trazodone (trazadone)? Trazodone (trazadone) is used to treat depression. For older adults, the half-life may be even longer due to reduced metabolism. Yes, you can overdose on trazodone, and it can be dangerous. If you will take Trazodone at bedtime it may reduce a risk of side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Learn why some wind turbines kill birds. Fortunately, trazodone is a great option for depression and even sleep problems, making it a popular antidepressant option. ingenuity swing replacement parts The product code(s) for this leaflet are: PL17780/0618, PL04425/0180, PL17780/0617, PL04425/0609. How much trazodone can I take for sleep? There's limited research on the best trazodone dosage for sleep. Exposure Information Service 8666847. Adult Initially 150 mg daily in divided doses, dose to be taken after food, alternatively initially 150 mg once daily, dose to be taken at bedtime, increased if necessary to 300 mg daily; increased if necessary to 600 mg daily in divided doses, higher dose for use in hospital patients only. Sepehry and I had the honour of presenting our findings at the 85th Annual National Convention of the Canadian Psychological Association (CPA 2024) in Ottawa, Ontario. Advertisement In the Hollywood thriller. The dosage of trazodone varies depending on what it is being used for. Like with any medication, even with one that has a lower potential for abuse, you should only take trazodone as prescribed. Trazodone is commonly prescribed for the treatment of depression, anxiety, and insomnia. Standard hypnotics have been implicated in increased risk of motor vehicle accidents and memory problems (Leufkens et al In contrast, trazodone's adverse behavioral effects have rarely been studied. If you become pregnant during treatment with trazodone hydrochloride tablets, talk to your healthcare provider about registering with the National Pregnancy Registry for Antidepressants. Pregnancy Studies 8778972. Advertisement In the Hollywood thriller.
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Much lower doses produce toxic symptoms when combined with other drugs. Trazodone is a medication used in the management and treatment of major depressive disorder. Depression and anxiety can develop for no apparent reason, or they may be triggered by a life event such as a relationship problem, bereavement, or illness. - Cytochrome P450 3A inhibitors and inducers - Cytochrome P450 2D6 (CYP2D6) inhibitors - Side effects of antidepressant medication - Serotonin syndrome agents - Pharmacology antidepressants Trazodone is not a benzodiazepine, according to Drugs Trazodone is an antidepressant that treats chemical imbalances in the brain that are known to lead to major depressive di. After you stop with trazodone treatment, you should wait at least 14 days before taking an MAOI as well. In Canada - Call your doctor for medical advice about side effects. (2) Trazodone does not worsen supraventricular arrhythmias. It is thought to work by increasing the activity of serotonin in the brain. So that is the answer to the how much Trazodone is lethal for dogs question. Trazodone overdose symptoms can include long-lasting erections, trouble breathing, seizures, and heart rhythm issues. How much trazodone can I take for sleep? There's limited research on the best trazodone dosage for sleep. On May 29, up to 40 peop. Trazodone is used off-label for patients with insomnia. lilith trine jupiter Breastfeeding while taking trazodone: Information on the use of trazodone in breastfeeding is limited. Much like its effect on depression, trazodone can take multiple weeks to work for anxiety. Expert Advice On Improving Your Hom. 6 Symptoms can range from shivering and diarrhea to muscle rigidity, fever, and seizures. You may also report side effects at https://wwwgov. Trazodone is rapidly absorbed in the gastrointestinal tract after oral administration, with a bioavailability ranging from 63-91% 9 and an AUC0−t of 18193 17 Food may impact absorption in a variable fashion, and may sometimes lead to decreases in the Cmax of trazodone. Trazodone is used in the treatment of Depression. It comes in 50 mg, 100 mg, 150 mg, and 300 mg scored white, round tablets. You don’t have to buy expensive herbicides to kill weeds in the cracks of a driveway or sidewalk. Do not attempt to give trazodone to your dog without first consulting with your vet. Trazodone was developed by Italian pharmaceutical company Angelini Research Laboratories in the 1960s and was subsequently patented in many countriesS. Expert Advice On Improving Your. Pregnancy Studies 8778972. redmond bright horizons Trazodone overdose occurs when someone takes more than the normal or recommended amount of this medicine, either by accident or on purpose. It can also help with insomnia and chronic pain. See also PRECAUTIONS, Drug Interactions. Effects on the respiratory system is very common for people suffering from trazodone overdose. 12 In our patient, manic episode was developed after 1 week of treatment with 50 mg/day. For older adults, the half-life may be even longer due to reduced metabolism. Omg kill me now! I'm a recovering heroin addict been clean 9 years and feel as though weaning off Trazodone is worse. Small amounts of trazodone have been found in breast milk. You can learn more about compounded medications here. You should talk about this possibility with your health care provider. In this article, we go over the best natural ways to control and kill weeds. Trazodone lasts in your system for approximately 42 hours after the last dose, with its effects lasting for about 5 to 9 hours. Rapidly and almost completely absorbed from the GI tract; peak plasma concentration usually attained within 1-2 hours Antidepressant effects evident within 1 week; optimal antidepressant effects usually attained after 2-4 weeks. Advertisement In the Hollywood thriller. Tell your doctor about the allergy and what signs you had. For example, if a dog weighs 23 pounds the animal dose of trazodone is in the 23 mg to 70 mg range. This includes your doctors, nurses, pharmacists, and dentists. When a furry family member is host to these tiny pests, you can soon find your entire. An early randomized, double-blind, placebo-controlled study of geriatric patients with unipolar depression demonstrated that. In severe cases, this can be life-threatening. Choosing recovery close to home means your support system is just a few miles away. com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. newcomers obituaries Some dogs may be more sensitive than others to its effects. Choosing recovery close to home means your support system is just a few miles away. Trazodone works by causing an increase in levels of serotonin, a neurotransmitter that helps maintain mental balance. Humans are apex predat. Yes, you can overdose on trazodone, and it can be dangerous. Do not drink alcohol while taking trazodone. Combining the use of trazodone and an MAOI may lead to high blood pressure, confusion, and tremors. Advertisement In the Hollywood thriller. The drug later gained various off-label (non-approved) uses, including in the treatment of anxiety, bulimia, chronic pain, dementia. The authors, editors, producers, and contributors shall have no liability, obligation, or responsibility to any person or entity for any loss, damage, or adverse consequences alleged to have happened directly or indirectly as a consequence of material on this website. Some people kill animals because they want to use the animals for food or clothing, while other people kill animals because they find it challenging and fun. in 24 hours is an overdose. Your doctor will tell you how long treatment with trazodone will last. Fortunately, trazodone is a great option for depression and even sleep problems, making it a popular antidepressant option. Trazodone can be lethal if more then the prescribed dose is taken, but instances are rare, according to MedlinePlus. These side effects may go away during treatment as your body adjusts to the medicine. Trazodone is a medication that is commonly used to treat anxiety and depression in humans. Here are some tips to safely and effectively. • Antidepresants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients (5. do you think you know your snakes? Well, let's see how you do in telling how exactly they kill their prey. The product code(s) for this leaflet are: PL17780/0618, PL04425/0180, PL17780/0617, PL04425/0609. symptoms of overdose.
Do not drink alcohol while taking trazodone. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the treatment of. You'll hopefully be more relaxed about things that used to worry you. Vomiting Trazodone overdose can also lead to serotonin syndrome, a condition characterized by excessive accumulation of serotonin in the body. Dosage and Administration. oziach osrs Trazodone is a drug used to treat anxiety and depression. Do not drive, use machinery, or do anything that needs mental alertness until you know how trazodone affects you. Do not chew or crush trazodone hydrochloride tablets. Even at these low doses, trazodone may be able to help you fall asleep and stay asleep. Trazodone Pill Images. Both options are free, confidential, and available 24 hours a day. tom clancy wikia Trazodone will not change your personality, it will simply help you feel like yourself again. A trazodone overdose can be characterized by various life-threatening symptoms. To achieve simultaneous determination of two antidepressants, TRZ and DOX, a novel detection system was designed: a. The recommended trazodone dosage for dogs generally ranges from 1 to 19 milligrams per kilogram of the dog's mass, per day. You may feel that trazodone is not working for you straightaway. sara jane drescher This is why finding a medication that works for you is important. If you need a handy way to kill weeds, especially those that grow in sidew. Desyrel side effects. Trazodone hydrochloride tablets.
What Happens If You Take A Lethal Dose Of A Drug? Taking lethal doses of a drug, including those prescribed by a doctor, can be deadly. If your doctor prescribed trazodone for depression, you should not assume that the treatment is ineffective until you've given it the full 6 weeks to work. Thunderstorms have killed another 40 people in Uttar Pradesh, Bihar, and Jharkand. Trazodone should be used with caution in pets with certain medical conditions, including heart disease, liver disease, kidney disease, and angle-closure glaucoma Although trazodone can cause several short- and long-term side effects, some of these effects can be managed with easy-to-implement strategies Dimitriu shares the following advice for managing trazodone side effects in elderly patients: Take it at night. While the potential for trazodone abuse is fairly low, any amount over 600 mg. Have attempted with these and this is what happened: started with 10 50 mg tabs and my body rejected them almost immediately by throwing up. Oral route (Tablet, Extended Release; Tablet) Antidepressants increased the risk compared to placebo of suicidal thinking and behavior in children, adolescents, and young adults with major depressive disorder (MDD) and other psychiatric disorders in short-term studies. Trazodone is a serotonin-2 antagonist/reuptake inhibitor with moderate histamine-1 (H1) receptor antagonism properties (Sheehan 2009). Stress is unlikely to result in death for the average person, but there are long-term effects of stress to consider. Trazodone: learn about side effects, dosage, special precautions, and more on MedlinePlus A small number of children, teenagers, and young adults (up to 24 years of age) who took a. Objective: This retrospective study examines whether long-term use of trazodone, an SWS enhancer, is associated with delayed cognitive decline. As with all antidepressants, if you suddenly stop taking trazodone, it can result in some uncomfortable withdrawal symptoms. Despite the lack of evidence, trazodone is generally considered to have a low potential. dead relative tattoo ideas Is there a coupon for trazodone? expand_more. Talk to your healthcare provider about the risk to your unborn baby if you take trazodone hydrochloride tablets. There is no conclusive information on the amount of trazodone it takes to fatally overdose. You may report side effects to Health Canada at 1-866-234-2345. The effect of short-term administration of ritonavir (200 mg twice daily, 4 doses) on the pharmacokinetics of a. Learn more about how trazodone is compared to ambien as a sleeping pill. If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their online tool. Research on the long-term efficacy and safety of trazodone for insomnia is. For some people, even lower doses may prove effective and cause fewer side effects. If dogs have too much Trazodone, it can actually kill them. This information from Lexicomp explains what you need to know about this medication, including what it's used for, how to take it, its side effects, and. Do not chew or crush trazodone hydrochloride tablets. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat Stop taking Desyrel and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a heart condition that can lead to arrhythmias Benzodiazepines, such as Xanax. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocols (PRISMA-P) 2015 statement 20, the protocol was previously registered on November 29, 2020 Trazodone is used to manage canine and feline anxiety issues Home. You may report side effects to Health Canada at 1-866-234-2345. If your symptoms feel severe, such as trouble breathing, extreme confusion, or vomiting, contact Poison Control online or at 1-800-222-1222 or seek immediate medical care. lowlights with blonde mCPP leads to breathing trouble, feelings of suffocation, heart palpitations, decreased motor control, confusion, OCD, bipolar behavior, mania and alcohol cravings Do not chew or crush Trazodone Hydrochloride Tablets. Residual insomnia in treated MDD. Initial 150 mg/day PO divided q8-12hr. There are 650 drugs known to interact with trazodone, along with 8 disease interactions, and 1 alcohol/food interaction. Depression and anxiety can develop for no apparent reason, or they may be triggered by a life event such as a relationship problem, bereavement, or illness. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Trazodone has an average rating of 6. Trazodone's potent α 1-adrenergic blockade may cause some side effects like orthostatic hypotension and sedation. Purpose Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. If you take too much trazodone hydrochloride tablets, call your healthcare provider, your Poison Control Center at 1-800-222-1222, or go to the nearest emergency room right away. In severe cases, this can be life-threatening. See also PRECAUTIONS, Drug Interactions. These include: Other antidepressants; Antihistamines; Sedatives; Pain relievers, and muscle relaxants; Taking alcohol with trazodone; How Much Trazodone is Necessary to Overdose? An overdose of trazodone can be fatal. Although it is FDA-approved only for use in the treatment of major depression, trazodone, a drug created in the 1960s [], is widely used off-label to control agitation and insomnia in Alzheimer's disease (AD) [] and in anxiety, schizophrenia, bulimia, substance abuse, fibromyalgia [], and post-traumatic stress disorder [1, 4] Trazodone is a medication that is commonly used to treat anxiety and depression in humans. Trazodone is used in the treatment of Depression. Trazodone Interactions. If you take too much trazodone hydrochloride, call your doctor or go to the nearest emergency room right away. com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.